Klinefelter’s syndrome

Klinefelter’s syndrome is a rare condition affecting 1 in 500 to 1 in 1000 men. Men with Klinefelter’s syndrome have two X (female) chromosomes and one Y (male) chromosome (XXY) instead of a single X and single Y chromosome (XY). Symptoms of Klinefelter’s syndrome include longer legs, a higher voice, a thinner than average beard, smaller than normal testicles, and the inability to produce sperm (infertility). Men with this syndrome also have lower levels of male hormones and higher levels of female hormones. Men with Klinefelter’s syndrome have a greater risk of developing breast cancer.

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